职位描述
Laboratory Introduction
The Kundu Lab studies functional microbiomics and stem cells, particularly neuronal and intestinal stem cells. We have recently shown that maternal gut microbiota programs fetal stem cells, revealing mechanisms by which microbial metabolites during pregnancy impact offspring development, long-term health, behavior and disease recovery (Dang et al, Cell Stem Cell, 2025). Additionally, we have uncovered a unique symbiotic mechanism by which colonic crypt microbiota safeguards the host against colorectal cancer initiation (Zhang et al, Nature Microbiology, 2025). We are currently investigating how gut microbiota–stem cell interactions shape complex physiological and pathophysiological processes, such as development, ageing, and cancer. Our hypothesis-driven research employs an integrative systems biology approach, combining gnotobiotic and transgenic animal models, multi-omics, neurosphere/organoid systems, and human cohort studies.
Major Research Projects
1. Influence of maternal gut microbiota on child’s neuronal and intestinal stem cells– link to disease susceptibility later in life.
2. Role of gut microbiome- intestinal stem cell crosstalk in tumorigenesis.
3. Importance of Bacteriophages in modulating the gut microbiome: impact on host stem cells.
Open Position
Lab Manager
Main Responsibilities
1) Support PI in overall running of the Laboratory.
2) Execute purchase orders, reimbursements, maintain laboratory equipment, and facilitate members of the lab in conducting experiments.
3) Communicate with different groups and departments for example HR, Finance and Purchase departments to support laboratory operations.
4) Communicate with collaborators and facilitate the procurement of biological samples.
5) Maintain logs for chemicals, biological samples and biobank for the laboratory.
Qualifications
1)Bachelor / Master degree in biology or life sciences is required.
2)Excellent communication skills in English and Chinese with good professional ethics, and personality are desired.
3) A strong learning ability, coordination skills and good teamwork spirit are preferred.
4)Experience in biological laboratory procedures and ability to execute laboratory operations are desired.